Page 176 - Livre électronique du congrès des RFTP 2022

P107
PREDICTORS OF SEVERITY IN COVID-19 PATIENTS

H. KWAS, A. GANNOUNI, S. MAJDOUB, W. MEDI.

PULMONOLOGY DEPARTMENT. UNIVERSITY HOSPITAL OF GABES, TUNISIA.

INTRODUCTION : Tunisia was affected, as were other countries, by the coronavirus
disease 2019 (COVID-19) pandemic. Many risk factors of COVID-19 severity have been
described, but data on infected patients in North Africa are limited.

AIM:To identify predictors of disease severity in patients with COVID-19.
METHODS : In this retrospective and observational study, we included all patients
with confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection, admitted to University Hospital in Gabes between November 2020 until
January 2021. The factors determining the prognosis are admission to an intensive
care unit with or without the use of invasive ventilation and death.
RESULTS : We reported 200 patients (50.5% were men) with confirmed SARS-CoV-2
infection. The median age was 66 years. Seventy eight percent of patients had at least
one comorbidity, the most common of which were hypertension (39.5%) and diabetes
mellitus (34%). Dyspnea (80.5%), cough (69.5%) and fever (67.5%) were the most
common presenting symptoms. Severe pneumonia was present in 37.5% of COVID-
19 patients. Univariate logistic regression analysis indicated that advanced age,
hypertension, lymphopenia, anemia, elevated CRP and D-dimer levels and the
consultation after 7 days of onset of symptoms were risk factors for the severity of
COVID-19 pneumonia (P = .005, .002, .047, .021, .02, .001 and .001, respectively).

CONCLUSION : Age, blood pressure, complete blood count and routine biochemical
tests would appear to be important parameters for the evaluation of the severity of
COVID-19 pneumonia.

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