Page 180 - Livre électronique du congrès des RFTP 2022

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IMPACT OF OBESITY ON THE INTRA-HOSPITAL EVOLUTION
OF PATIENTS WITH SARS-COV-2 PNEUMONIA

E. BEN JEMIA, S. RJEB, N. KHALFALLAH, H. OUERTANI, J. BEN AMAR, H. ZAIBI, H. AOUINA
CHARLES NICOLLE HOSPITAL OF TUNIS

BACKGROUND : Obesity has been widely reported to be associated with the disease
progression of SARS-CoV-2 pneumonia and research into this association has yielded
conflicting results. Therefore, we examined the impact of obesity on the intra-hospital
evolution of patients with SARS-COV-2 pneumonia.
METHODS : A retrospective and comparative study was conducted for 6 months in
Charles Nicolle Hospital of Tunis. Patients with confirmed SARS-COV-2 moderate to
severe pneumonia were included. We calculated body mass index (BMI, kg/m2) and
we identified 2 groups: G1: obese patients (BMI ≥ 30 ; n=66) and non-obese patients
(BMI<30 ; n=25).

RESULTS : We included 91 patients with sex ratio at 1.1, an average age at 61± 13 years
[22-96 years] and BMI’ mean at 28 ± 5 kg/m2 [21-43 Kg/ m2]. Obese patients were
younger 61years vs 68 years; p=0,02) with BMI mean at 31.5 kg/m2. Comorbidities
didn’t differ between groups (p=0,8). Severity of acute infection was similar in both
groups (p˃0.05)

Obesity was associated with poor outcomes (OR = 0.667, 95% CI [0.240–1.849]). In fact,
hospitalization in intensive care unit was necessary for 14 obese patients G1 vs 6 non-
obese patients; p=0,42. Mortality was higher in obese patients (G1: 13 patients vs G2 :7
patients; p=0,5). Hospital stay was similar in both groups (12 days vs 13 days; p=0,54).

CONCLUSION : According to the literature, obesity is responsible for poor
intrahospital evolution during SARS-COV2 acute infection.

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