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              SMOKING INTENSITY AND QUALITY OF LIFE OF COPD
              PATIENTS

              S. KHALDI1, K. DERBEL1, B. BARKOUS1, F. GUEZGUEZ1, A. SAYAHI1, S. ROUATBI1,2
              1-  DEPARTMENT OF    PHYSIOLOGY AND    FUNCTIONAL  EXPLORATION OF    FARHAT HACHED
              HOSPITAL OF SOUSSE
              2- LABORATOIRE DE RECHERCHÉ RESEARCH LABORATORY, LR12SP09

              INTRODUCTION : Quality of life (QoL) evaluation is a useful tool to measure outcomes
              of tobacco smoking. Understanding the relationship between them is important to
              improve motivation to smoking cessation and for treatment outcomes.

              Objective: Assess association of cigarette smoking intensity with quality of life in
              COPD patients.
              METHODS : We enrolled a cross sectional study including 105 COPD patients in the
              Functional Exploration department of Farhat Hached Hospital. Anthropometric and
              clinical characteristics were assessed by a standard medical questionnaire. Tobacco
              consumption was estimated in pack years. Life quality was assessed according to the
              ST. GEORGE'S RESPIRATORY QUESTIONNAIRE (SGRQ). All subjects underwent the
              spirometry with measurement of Forced expiratory volume in one second (FEV1%)
              and Forced vital capacity (FVC %). COPD is confirmed when the ratio FEV1/FVC post
              bronchodilator test <0.7.

              RESULTATS : Mean age was 63.8 ± 10.3 years and 87.6% were males. Median smoking
              intensity (pack-years) and FEV1 (L) were 51.5 [37; 70] and 1.24 [0.87; 1.61] respectively.
              In this study, 1%, 71.4%, 22.9% and 4.8% of the patients had GOLD stages 1, 2, 3 and 4,
              respectively. Mean  SGRQ score was 35.3±12.7. A statistically significant correlation
              between smoking intensity and SGRQ score was found (p= 0.032 and

              r= 0.220).

              CONCLUSION : Low QoL is associated with higher smoking intensity. This finding can
              raise awareness of both smokers and clinicians to become more conscious of the
              sub-clinical outcomes of tobacco  smoking and  to encourage  smoking cessation
              programs.













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