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HEALTH RELATED LIFE QUALITY AND BRONCHODILATOR
ADHERENCE IN COPD PATIENTS

K. DERBEL, B. BARKOUS, F. GUEZGUEZ, S. KHALDI, A. SAYHI, S. ROUATBI
PHYSIOLOGY AND FUNCTIONAL EXPLORATION DEPARTMENT, FARHAT HACHED HOSPITAL,
SOUSSE- TUNISIA

INTRODUCTION : Chronic obstructive pulmonary disease (COPD) patients frequently
suffer from continuous respiratory symptoms such as mainly dyspnea and, therefore,
experience substantial limitations in their daily life despite their care.
Objective: Assess the relationship of health related life quality (HLQ) and adherence
to bronchodilators in a group of COPD patients.

METHODS : It was a cross sectional study including 26 COPD patients treated by
bronchodilators (short and long acting β2 agonists and inhaled corticosteroids). They
answered two questionnaires: COPD assessment test (CAT) to evaluate their HLQ and
GIRERD questionnaire to evaluate their adherence to treatment. Pearson product-
moment correlation coefficient (r) evaluated CAT and GIRERD scores correlation.

RESULTS : Mean age was 66 ± 9 years and 96% were males. In this study, 12%, 19%,
50% and 19% of the patients had GOLD stages 1, 2, 3 and 4, respectively. Mean CAT
and GIRERD scores were 19 ± 7 and 2 ± 1, respectively. Only 27% of the patients were
good adherent to their bronchodilators and 50% had severe HQL (CAT scores > 20).
There was a statistically significant correlation between CAT and GIRERD scores (p=
0.027 and r= 0.434).

CONCLUSION : The lack of bronchodilator adherence in COPD patients seems to
generate negative effects on their perceived physical well being, which impairs their
HQL.

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