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ASSOCIATION BETWEEN ESTIMATED LUNG AGE AND LIFE
QUALITY IN COPD PATIENTS

K. DERBEL, S. KHALDI, B. BARKOUS, A. SAYHI, F. GUEZGUEZ, S. ROUATBI
PHYSIOLOGY AND FUNCTIONAL EXPLORATION DEPARTMENT, FARHAT HACHED HOSPITAL,
SOUSSE- TUNISIA

INTRODUCTION: Spirometric profiles of patients with chronic obstructive pulmonary
disease (COPD) are usually impaired and could reveal an increased lung age (LA).
OBJECTIVE: Evaluate a possible relationship between LA and daily life quality in
COPD patients.

METHODS: A cross sectional study including 135 COPD patients was performed. Life
quality was assessed according to the COPD assessment test (CAT). Patients
underwent spirometry and the following data were collected: first second expiratory
volume (FEV1), forced vital capacity (FVC). LA was estimated using FEV1 with a
specific formula for North African patients.

RESULTS: One hundred thirty-five (n= 135) COPD patients (120 males (89%)) were
included in the study. Mean age of the sample was 64±10 years. Median FEV1 (%) and
FVC (%) were 37 [27 ; 52] and 59 [47 ; 72] respectively. GOLD stages were mild,
moderate, severe, and very severe in 3%, 62.2%, 27.4% and 7.4% of the patients,
respectively. Median LA was 84 [70 ; 93] and 86% of the patients had a LA higher than
their chronological age. Mean CAT score was 18±7. There was a statistical Spearman
correlation of CAT score and LA (p<0.001 and r=453).

CONCLUSION: LA is a good surrogate of the lung function decline in COPD and could
result in a poor respiratory prognosis due to the lower health-related quality of life.

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